Monomethyl lithospermate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Monomethyl lithospermate has potential antiviral activity, alleviating ischemic stroke injury in vivo in middle cerebral artery occlusion mice by activating PI5K/Akt signaling and protecting oxygen-glucose deprivation/reoxygenation-induced SHSY-3Y cells in vitro.

Monomethyl lithospermate has potential antiviral activity, alleviating ischemic stroke injury in vivo in middle cerebral artery occlusion mice by activating PI5K/Akt signaling and protecting oxygen-glucose deprivation/reoxygenation-induced SHSY-3Y cells in vitro. Monomethyl lithospermate could improve the viability of SHSY-5Y cells, inhibit mitochondrial membrane potential (MMOP) collapse, and inhibit cell apoptosis. Monomethyl lithospermate also reduced the level of oxidative stress in the brain tissue of middle artery occlusion (MCAO) rats and improved nerve damage in ischemic stroke (IS) rats.

Immunofluorescence Cell Line:SHSY-5Y cells Concentration:5, 10, and 20 μM Incubation Time:12 hours Result:Inhibited the mitochondrial membrane potential (MMOP) collapse and apoptosis of SHSY-5Y cells induced by oxygen and glucose deprivation/Reoxygenation (OGD/R) treatment.

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Others

Other Targets

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933054-33-2

552.5

C28H24O12

>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years